Benoît Zuber

The paper evaluates the synaptic maturity of SH-SY5Y cells after differentiation and finds they lack functional synapses despite some presynaptic features.

This study improves human iPSC-derived motor neuron synapse formation using optimized differentiation and glutamatergic modulators, resulting in functional and structurally mature neuronal networks.

This paper introduces a genetically encoded FerriTag system for labeling target proteins in live cells for cryo-electron tomography, enabling precise localization with high contrast.

This study identifies ANTXR2 as the receptor for C. perfringens NetF toxin, revealing structural insights into its binding mechanism and pore formation.

The paper compares CEMOVIS and FIB-milling for cryo-EM sample preparation, showing CEMOVIS provides more imageable area with comparable structural preservation.

The paper presents high-resolution cryo-EM structures of aerolysin pre-pore and pore in a membrane-like environment, revealing key interactions and constriction rings relevant for nanopore sensing.

The paper introduces CryoVesNet, a framework for automated synaptic vesicle segmentation in cryo-ET data, improving accuracy and efficiency compared to manual methods.

The paper uses cryo-electron tomography to sequence events during synaptic vesicle exocytosis and identifies how tether formation and connector dissolution are regulated by stimulation and spontaneous fusion rate.

The paper shows that sustained WT1 expression impairs cardiomyocyte maturation and leads to their transformation into epicardial cells in zebrafish.

The paper develops a staining method for SBFSEM that avoids uranyl acetate, providing high contrast and reducing specimen charging without radioactive substances.