Impaired Complex I dysregulates neural/glial precursors and corpus callosum development revealing postnatal defects in Leigh Syndrome mice
Sahitya Ranjan Biswas, Porter L. Tomsick, Colin Kelly…·Alicia M. Pickrell
This study examines neural/glial precursor and corpus callosum development in Leigh Syndrome mice, revealing impaired Complex I function disrupts brain growth before neurodegenerative symptoms appear.