Alia O. Alia

This study uses proximity labeling to compare the interactomes of pyroglutamate-modified and unmodified amyloid beta in AD and control hippocampus, identifying unique and shared protein interactions.

The paper performs proteomic analysis of human leptomeningeal matrisome in Alzheimer's disease and controls, identifying disease-associated changes in ECM proteins and signaling pathways.

This study investigates whether ACE1 influences Aβ degradation or amyloid plaque accumulation in 5XFAD mice, finding no effect on amyloid burden or neuroinflammation.

This study shows that neuronal ACE1 knockout in mice causes hippocampal RAS dysregulation and vascular loss without affecting motor skills.