Zigang Song

This study uses molecular dynamics simulations to show that specific THz frequencies enhance conductance of Kv1.2 and Nav1.5 ion channels by affecting ion motion in selectivity filters.

The paper outlines a simulation protocol to identify THz frequencies affecting ion channels and finds a broad frequency band between 1 to 20 THz impacts CaV channels.

The paper evaluates variant effect predictions for ARSA gene variants, finding that a bootcamp-trained model outperformed others and that deep learning slightly improved performance over simpler methods.