Cancer BiologybioRxivPreprint
HSF1 excludes CD8+ T cells from breast tumors via suppression of CCL5
Curteisha LeeAnn Jacobs, Sakhi Shah, Wencheng Lu…·Richard L. Carpenter
This study shows HSF1 suppresses CD8+ T cell infiltration in breast tumors by reducing CCL5 expression, thereby preventing immune-mediated tumor destruction.
DOI 10.1101/2022.05.12.491688