Leqiang Sun

This study uses SPIDER-Seq to create a spatial multi-omic atlas of mouse prefrontal cortex, revealing modular organization and neural transmission mechanisms.

The paper develops MiP-Seq, a multiomics in situ sequencing method, to analyze spatial gene profiles, mutations, and RNA modifications at single-cell resolution.

The paper develops a multi-fluorescent rabies virus tracing tool to map corticothalamic projection neuron subsets in the primary visual cortex, revealing their layer-specific distribution and multi-target connectivity.