Liang Li

This study shows that Afadin is essential for sorting retinal neuron types into correct cellular layers, but not for their survival or synaptic partner selection.

This study shows that GPX4 overexpression in RGCs promotes optic nerve regeneration and neuroprotection in glaucoma models.

This study identifies OPTN's role in axonal mitochondria transport and shows its loss contributes to neurodegeneration in models of ALS and NTG.

This study identifies Muller glial cells as sensitive to diabetes and shows that Zfp36 expression in these cells can protect against diabetic retinopathy.

The paper shows that Mettl14-mediated m6A modification is critical for cell cycle progression of late-born retinal progenitor cells, preventing cell cycle arrest and neuronal death.

This paper establishes a rhesus macaque model of glaucomatous neurodegeneration using silicone oil injection, showing RGC death, optic nerve degeneration, and functional deficits similar to human glaucoma.

The paper develops a multi-fluorescent rabies virus tracing tool to map corticothalamic projection neuron subsets in the primary visual cortex, revealing their layer-specific distribution and multi-target connectivity.

This paper develops a reversible mouse model of secondary glaucoma using silicone oil and validates it for testing neuroprotective therapies.