Author

Samuel Leppiniemi

University of HelsinkiORCID 0009-0006-3684-0206Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Research Focus:eQTL / molecular QTL mapping· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Sampsa HautaniemiiD· 2 shared Anna VähärautioiD· 1 shared Anniina FärkkiläiD· 1 shared Anu AniliD· 1 shared Chuqi LeiiD· 1 shared Daria AfentevaiD· 1 shared Déborah BoyenvaliD· 1 shared Eva Daniela Mendoza OrtiziD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Sampsa HautaniemiORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 20, 2025

Proteome profiling reveals HES1-driven mitotic catastrophe in ovarian serous carcinoma

Jie Bao, Sanna Pikkusaari, Jun Dai…·Jing Ping Tang

This study identifies BX-912 as a therapeutic agent for ovarian serous carcinoma, revealing HES1 as a target and showing synergistic effects with olaparib.

DOI 10.1101/2025.08.20.671256

humanproteomics

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BioinformaticsbioRxivPreprintJul 28, 2025

SegmentQTL: Identifying genetic variants influencing molecular phenotypes in copy number-driven cancers

Samuel Leppiniemi, Daria Afenteva, Yilin Li…·Taru Muranen

SegmentQTL improves molQTL analysis in copy number-driven cancers by incorporating breakpoint information to reduce false discoveries and refine associations.

DOI 10.1101/2025.07.28.667150

whole-genome sequencingstatistical model

𝕏 PostBluesky