PathologybioRxivPreprint
Age-associated spontaneous activation of BMP signaling inhibits the canonical Wnt pathway through ICAT to promote osteoarthritis
Bhupendra Kumar, Sayeda Fauzia Iqbal, Ankita Jena…·Amitabha Bandyopadhyay
This study shows that age-related BMP signaling activation inhibits Wnt/{beta}-catenin through ICAT, leading to osteoarthritis in mice.
DOI 10.1101/2024.10.02.616036