Akshay Kumar

This study links ER stress and impaired NAD biosynthesis via QPRT to reduced oocyte quality and shows that NMN supplementation improves oocyte function and early embryonic development.

This study identifies HIPK2 and IKKβ as kinases that phosphorylate TAp63α, stabilizing it during the oocyte DNA damage response and enhancing oocyte survival.

This study identifies CDK1 as a critical regulator of DNA repair in dictyate-arrested oocytes, showing it facilitates RAD51-mediated homologous recombination to protect against genotoxic stress.

This study identifies the DGAT1-PANK2-NRF2 axis as critical for lipid droplet remodeling, redox balance, and oocyte quality, with dysfunction linked to age-related decline.