BioengineeringeLifePeer-reviewed
The flexible stalk domain of sTREM2 modulates its interactions with brain-based phospholipids
David Saeb, Emma E Lietzke, Daisy I Fuchs…·Kayla G. Sprenger
This study identifies the flexible stalk domain of sTREM2 as critical for differential ligand binding and neuroprotection in Alzheimer's disease through molecular dynamics simulations.