Ziyang Shen

This paper describes a method to recover and biobank CD34+ hematopoietic stem cells from clinical apheresis waste for hemoglobinopathy research, showing comparable yields and viability to peripheral blood samples.

This paper uses AI to identify and validate non-coding regulatory variants affecting RHD expression, showing strong agreement between predictions and experimental results.

CloneCoordinate is an open-source electronic lab notebook for DNA cloning that improves collaboration and efficiency through task management and data standardization.

This paper discovers and characterizes SH6, a small molecule degrader of ZBTB7A that increases fetal hemoglobin expression in erythroid cells and shows therapeutic potential for β-hemoglobinopathies.