Jun Liu

This paper describes a method to recover and biobank CD34+ hematopoietic stem cells from clinical apheresis waste for hemoglobinopathy research, showing comparable yields and viability to peripheral blood samples.

This paper uses AI to identify and validate non-coding regulatory variants affecting RHD expression, showing strong agreement between predictions and experimental results.

This paper discovers and characterizes SH6, a small molecule degrader of ZBTB7A that increases fetal hemoglobin expression in erythroid cells and shows therapeutic potential for β-hemoglobinopathies.

This study shows that Hippo pathway-mediated YAP1/TAZ inhibition is essential for pancreatic endocrine specification and differentiation, but not for beta-cell function.

This study investigates the role of YAP1 and TAZ in pancreatic inflammation and evaluates the therapeutic potential of VT-104 in a mouse model of pancreatitis.