Author

Ying-Yu Chen

Johns Hopkins UniversityORCID 0009-0006-6725-8593Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ying-Yu Chen1 paper · Biodiversity Research Center, Academia Sinica

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Jennie J. Cao· 1 shared Jina ParkiD· 1 shared John D. Outen· 1 shared Julia AniD· 1 shared Michael J. TopperiD· 1 shared Ray-Whay Chiu Yen· 1 shared Stephen B. BayliniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Jennie J. Cao

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1 paper

Recent·Most cited

Cancer BiologyCell ReportsPeer-reviewedMay 19, 2025

MYC plus class IIa HDAC inhibition potentiates mitochondrial dysfunction in non-small cell lung cancer

Jina Park, Ying-Yu Chen, Jennie J. Cao…·Michael J. Topper

This study identifies that combining MYC inhibition with class IIa HDAC inhibition enhances mitochondrial dysfunction and reduces viability in NSCLC cell lines.

2 citations

humanbulk RNA-seq

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