Emily Langore

This study investigates the role of disulfide bonds in the GluN1 subunit of NMDA receptors, showing their impact on trafficking and function, and introduces a method for synchronized release of NMDARs from the endoplasmic reticulum.

This paper develops a novel NMDA receptor open-channel blocker, K2060, showing improved efficacy and reversibility compared to existing drugs like memantine and dizocilpine.

This study shows that structural changes in the ligand-binding domains of GluN1 and GluN2A subunits independently regulate early trafficking of NMDARs and that surface expression does not always correlate with agonist sensitivity.