Author

Sem Asmelash

Yale UniversityORCID 0009-0006-7108-1866Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Jeffrey D. MandelliD· 1 shared Jeffrey Nicholas FiskiD· 1 shared Jeffrey P. TownsendiD· 1 shared Kira A. GlasmacheriD· 1 shared Mary F Summers· 1 shared Vincent L. CannataroiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Jeffrey D. MandellORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJun 30, 2026

Stepwise Evolution and Epistatic Interaction of Driver Mutations from Endometrial Hyperplasia to Carcinoma

Mary F Summers, Kira A. Glasmacher, Sem Asmelash…·Vincent L. Cannataro

This study analyzes the evolutionary dynamics of driver mutations during endometrial hyperplasia to carcinoma progression, revealing differences in selection pressures and epistatic interactions between mutation pairs.

DOI 10.64898/2026.06.05.730445

humanDNA methylation

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