Author

Nicolas Floc’h

AstraZeneca (United Kingdom)ORCID 0009-0006-8557-2199Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Ainsley Mike AntaoiD· 1 shared Alessandro VasciaveoiD· 1 shared Alexander ChuiiD· 1 shared Alexander L.E. WangiD· 1 shared Alix Schwiening· 1 shared Anca M. FarcasiD· 1 shared Andrea CalifanoiD· 1 shared Andrei ProdaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Ainsley Mike AntaoORCID

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2 papers

Recent·Most cited

Cancer BiologyThe Journal of Experimental MedicinePeer-reviewedApr 28, 2026

A forward genetic screen identifies Sirtuin1 as a driver of neuroendocrine prostate cancer

Francisca Nunes de Almeida, Alessandro Vasciaveo, Arianna Giacobbe…·Cory T. Abate-Shen

The paper uses a forward genetic screen in a mouse model to identify Sirtuin1 as a driver of neuroendocrine prostate cancer, showing its role in promoting NEPC and potential as a therapeutic target.

2 citations

mousebulk RNA-seq

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GenomicsbioRxivPreprintJan 25, 2024

10x Genomics Gene Expression Flex is a powerful tool for single-cell transcriptomics of xenograft models

Oriol Llorà-Batlle, Anca M. Farcas, Doreth Fransen…·Ultan McDermott

The paper demonstrates that the 10x Genomics Gene Expression Flex protocol can profile mixed human and mouse cells in xenografts by using combined probe sets and a pipeline to remove cross-reactive signals.

13 citations

humanmouse

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