ImmunologybioRxivPreprint
Metabolic Reprogramming of Pathogenic CD4+ T Helper Cells Attenuates Inflammatory Bowel Disease Pathogenesis
Shravan Kumar Mishra, Leena M. Abdelrahman, Heidi M. Davidson…·Adebowale O. Bamidele
This study shows that metabolic reprogramming of Th1 cells via GSK3β inhibition reduces inflammation in IBD by suppressing glycolysis and cytokine production.