BiochemistrybioRxivPreprint
Structural Determinants of Catalytic Bias in an AMP-Forming Acetyl-CoA Synthetase from Syntrophus aciditrophicus
Selena Yaghoubi, David M. Dinh, Leonard M. Thomas…·Elizabeth A. Karr
This study identifies structural determinants of catalytic bias in SaAcs1, showing that residues G196 and T197 in the CoA-binding loop influence the preference for AMP formation.
DOI 10.64898/2026.07.06.736832