Author

Jie Luo

Shanghai Jiao Tong UniversityORCID 0009-0007-0002-8926Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jie Luo10 papers · University of Michigan

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:CRISPR screen· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Junkang An· 2 shared Shiyi ZhangiD· 2 shared Bingxue YangiD· 1 shared Dazhao LviD· 1 shared Jiahao QiuiD· 1 shared Kangfei Liu· 1 shared Longfei ZhaoiD· 1 shared Mengdi Wang· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPharmacology & Toxicology

Junkang An

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintMar 9, 2025

Integrating Literature Evidence to Enhance CRISPR-based Target Screening for Hand-foot Syndrome

Qiqi Yang, Bingxue Yang, Junkang An…·Shiyi Zhang

This paper introduces a dual-filter strategy combining literature-mined targets with CRISPR/Cas9 screening to prioritize credible drug targets for hand-foot syndrome, identifying ATF4 as a key regulator and forskolin as a potential therapeutic.

DOI 10.1101/2025.03.09.642163

humanCRISPR screen

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BiochemistrybioRxivPreprintMar 5, 2025

Automated Discovery of Therapeutic Biomaterial for Renally Impaired Hyperuricemia Patients by Natural Language Processing and Machine Learning

Xiaodong Zeng, Jiahao Qiu, Xin Gui Zhao…·Shiyi Zhang

The paper develops MatWISE, a framework using NLP and ML to discover a biomaterial for renally impaired hyperuricemia, identifying δ-MnO2 as a promising UA-lowering agent.

DOI 10.1101/2025.03.05.641578

mousedeep learning

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