Karun Mutreja

This paper develops a deep learning model to predict molecular alterations in never-smoker lung adenocarcinomas from histological images, achieving high accuracy for most features.

The paper identifies three subtypes of NS-LUAD using RNA-seq data and develops a 60-gene signature that predicts survival across subgroups.

This study identifies PrimPol as a key player in ICL traverse, showing its primase activity is required for DNA damage tolerance and that its absence increases sensitivity to ICL-inducing drugs.