Daniel D. Fusca

The paper investigates gene regulatory divergence in Caenorhabditis nematode hybrids, finding that cis-regulatory divergence disproportionately affects gene expression and contributes to sex-specific hybrid dysfunction.

The paper uses in vivo parallelized reporter assays in C. elegans to identify tissue-specific splicing regulatory sequences and their functional relevance.

The paper compares gene expression between two Caenorhabditis nematode species, finding that tissue-biased expression is conserved while sex-biased genes drive divergence.

The paper estimates speciation clocks in Caenorhabditis nematodes, finding post-zygotic reproductive isolation accumulates faster than pre-zygotic isolation.

The paper surveys Argonaute genes across 51 Caenorhabditis species, identifying gene gains, losses, and functional diversification, revealing dynamic evolution of small RNA pathways.

The paper investigates the dual role of H2AK119ub in regulating both H3K27me3-repressed and enhancer chromatin states in C. elegans.