Author

Timo Frömel

Goethe University FrankfurtORCID 0009-0007-1856-5359Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Ingrid FlemingiD· 2 shared Adarsh M. KumariD· 1 shared Aimo KanntiD· 1 shared Arne Hackspacher· 1 shared Astrid Brüggerhoff· 1 shared Astrid Kaiser· 1 shared Björn HäupliD· 1 shared Christina HesseiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

Ingrid FlemingORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintDec 12, 2025

Pericyte contact alters endothelial cell metabolism by promoting exchange of lactate through SLC16A3

Mahdieh Safarzad, Sebastian Kempf, Roman Vuerich…·Ingrid Fleming

This study shows that pericyte contact promotes endothelial cell metabolism by transferring lactate via SLC16A3, altering acetylome and lactylome, and enhancing EndMT-like processes.

DOI 10.64898/2025.12.10.693369

mouseproteomics

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BiochemistryJournal of Medicinal ChemistryPeer-reviewedJun 18, 2025

STRUCTURE-BASED DESIGN OF PROTACS FOR THE DEGRADATION OF SOLUBLE EPOXIDE HYDROLASE

Julia Schönfeld, Steffen Brunst, Ludmila Ciomirtan…·Kerstin Hiesinger

This paper designs and tests sEH-PROTACs to degrade soluble epoxide hydrolase, identifying PROTAC 23 as effective in degrading sEH in human macrophages.

11 citations

humanprotein structure

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