Author
Goethe University FrankfurtORCID 0009-0000-9445-9565Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Lin Zhang, Arnold Bolomsky, Omar S. Al‐Odat…·Ryan M. Young
This study identifies phosphorylation as a mechanism protecting oncogenic RAS from LZTR1-mediated degradation, with implications for targeting RAS stability in hematologic cancers.
Marius Külp, Mireia Osuna Lopez, Anna-Sophia Wiegand…·Michael A. Rieger
This study maps tRNA expression dynamics across human hematopoiesis using sc-STM-seq and identifies tRNAs linked to stemness, differentiation, and cell lineages.
Constanze Schneider, Gabriela Alexe, Lucy A. Merickel…·Kimberly Stegmaier
The paper identifies USP48 as a regulator of chromatin stability and DNA damage response to hypomethylating agents, showing its loss increases susceptibility to these drugs in AML.
Julia Schönfeld, Steffen Brunst, Ludmila Ciomirtan…·Kerstin Hiesinger
This paper designs and tests sEH-PROTACs to degrade soluble epoxide hydrolase, identifying PROTAC 23 as effective in degrading sEH in human macrophages.