Author

Yani Zhao

University of North Carolina at Chapel HillORCID 0009-0007-2779-7290Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Angie L. MordantiD· 1 shared C.H. ArrowsmithiD· 1 shared Dalia Baršytė-LovejoyiD· 1 shared Devan J. ShelliD· 1 shared Fengling LiiD· 1 shared Jacqueline L. Norris-DrouiniD· 1 shared Jarod M. WaybrightiD· 1 shared Justin M. RectenwaldiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Angie L. MordantORCID

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1 paper

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedFeb 24, 2025

Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells

Mélanie Uguen, Devan J. Shell, Madhushika Silva…·Stephen V. Frye

The paper identifies UNC10013, a covalent ligand targeting SETDB1's 3TD domain, which reduces methyltransferase activity and shows selectivity in cells.

12 citations

experimental assaydrug response / drug discovery

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