Angie L. Mordant

This study shows that integrin α3β1 is essential for alveolar-capillary barrier formation by regulating epithelial differentiation during lung development.

The paper shows that pro-inflammatory microglia increase IRF7 levels and ethanol self-administration in rats during early abstinence, which is reduced by minocycline treatment.

This study shows USP7 inhibition disrupts proteostasis and tumor growth in triple negative breast cancer by stabilizing E3 ubiquitin ligases and affecting DNA repair pathways.

The paper identifies phosphorylation of endomembrane proteins in closed guard cells, suggesting their role in regulating stomatal closure.

This study examines temporal changes in extracellular vesicle (EV) protein cargo in burn-injury patients and mice, showing distinct immune reprogramming effects at early and late post-injury stages.

The paper identifies UNC10013, a covalent ligand targeting SETDB1's 3TD domain, which reduces methyltransferase activity and shows selectivity in cells.

The paper uses chemoproteomic profiling to identify selective anti-fungal kinase inhibitors targeting C. albicans CK1 homologs.

This paper uses stable isotope fingerprinting to link gut microbiota to their carbon sources and shows diet-induced substrate switching in vivo.

This study identifies MAPK14/p38α as critical for HGEC spheroid growth, shaping its transcriptomic, proteomic, and metabolomic landscapes and promoting tumorigenic properties.

This study examines the effects of sleep deprivation on synaptic vulnerability across developmental stages in mice, finding heightened sensitivity in juveniles and links to ASD risk.

This paper identifies and characterizes RA-0002034, a covalent inhibitor of CHIKV nsP2 protease, showing potent inhibition and selectivity against alphaviruses.