Author

Mario Fernández Comaduran

Montreal Neurological Institute and HospitalORCID 0009-0007-4002-5017Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Heather D. DurhamiD· 2 shared Javeria RizwaniD· 2 shared María VeraiD· 2 shared Sandra Minotti· 2 shared Suleima Jacob‐TomasiD· 2 shared Célia AleckiiD· 1 shared Chantelle F. SephtoniD· 1 shared Gene Wei-Ming YeoiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMolecular Biology

Heather D. DurhamORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedDec 30, 2024

Localized synthesis of molecular chaperones sustains neuronal proteostasis

Célia Alecki, Javeria Rizwan, Phuong Le…·María Vera

The paper shows that neuronal stress response involves localized synthesis of HSPA8 mRNA in dendrites to maintain proteostasis and prevent neurodegeneration.

26 citations

mousehuman

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NeuroscienceCell Stress and ChaperonesPeer-reviewedApr 1, 2024

Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS

Mario Fernández Comaduran, Sandra Minotti, Suleima Jacob‐Tomas…·Heather D. Durham

This study examines the effects of HDAC inhibitors and arimoclomol on HSP expression and disease biomarkers in ALS models, finding variable responses across different ALS variants and biomarkers.

12 citations

experimental assay

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