Heather D. Durham

The paper shows that neuronal stress response involves localized synthesis of HSPA8 mRNA in dendrites to maintain proteostasis and prevent neurodegeneration.

This study examines the effects of HDAC inhibitors and arimoclomol on HSP expression and disease biomarkers in ALS models, finding variable responses across different ALS variants and biomarkers.

This study identifies sacsin interactors involved in organellar transport and membrane composition, revealing their role in ARSACS pathogenesis.

This study investigates the role of NEFL splicing and balance in zebrafish motor neuron development and function, showing that disruption of isoform balance leads to motor deficits and interacts with TDP-43 mislocalization.