Isabelle Anselme

The paper shows that Gli signaling controls lumen retraction in the zebrafish spinal cord, which drives roof plate cell extension during development.

This study shows that TMEM67 is essential for proper dorsal spinal cord patterning in human organoids, with loss of TMEM67 disrupting interneuron specification and altering BMP4 signaling.

This study shows that ciliary dysfunction in human cerebellar organoids leads to overactivation of FGF/MAPK signaling, impairing neurogenesis and increasing progenitor proliferation.

This study compares the role of RPGRIP1L in human and mouse neural progenitor fate specification, finding distinct effects on motoneuron identity and SHH signaling.

This study identifies astrogliosis and neuroinflammation as pathogenic mechanisms underlying scoliosis in zebrafish caused by cilia dysfunction.

This study investigates the role of the ciliopathy gene Ftm/Rpgrip1l in mouse forebrain development, revealing its region-specific modulation of Hedgehog/Gli signaling in the diencephalon, hypothalamus, and eyes.

The paper introduces a method to visualize protein synthesis in zebrafish embryos by using a fluorescent reporter system to identify sites of translation.