Author

Praghadhesh Thiagarajan

Science for Life LaboratoryORCID 0009-0007-6469-9243Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Ana AgostinhoiD· 1 shared Bennie B. L. G. LemmensiD· 1 shared Bruno UriéniD· 1 shared Gemma Quijada· 1 shared Giovanni GiglioiD· 1 shared Hans BlomiD· 1 shared Jiří BártekiD· 1 shared Matilde Rodrigues da FonsecaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Ana AgostinhoORCID

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1 paper

Recent·Most cited

Cell BiologyThe EMBO JournalPeer-reviewedOct 7, 2025

Spatial mapping of DNA synthesis reveals dynamics and geometry of human replication nanostructures

Michael Hawgood, Bruno Urién, Ana Agostinho…·Bennie B. L. G. Lemmens

This study introduces 3D-SPARK, a method to visualize and quantify DNA replication dynamics at the nanoscale in 3D human cells, showing changes in replication structures under different conditions.

1 citation

humanDNA methylation

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