Ombeline Krekounian

This paper demonstrates that in vitro time-kill experiments with pharmacometric modeling can identify PK/PD targets equivalent to animal models for meropenem against P. aeruginosa, while quantifying inter-strain variability.

This paper develops and evaluates model ensembling and machine learning approaches to predict the first dose of amoxicillin in intensive care, finding that ensembling and ML outperform standard dosing.