NeurosciencebioRxivPreprint
Gating effects of a Cav2.3 calcium channel mutation linked to developmental and epileptic encephalopathy
Devon Khousakoun, Ivana Assis Souza, Laurent Ferron…·Gerald Werner Zamponi
This study examines the biophysical effects of a Cav2.3 channel mutation (L228P) linked to DEEs using whole-cell patch-clamp, finding a shift in voltage-dependent activation and inactivation towards hyperpolarized potentials.
DOI 10.64898/2026.05.25.727692