Gerald Werner Zamponi

This study shows ORL-1 interacts with Cav1.2, reducing its membrane expression without changing its biophysical properties.

This study identifies asymmetric π-H and π-π quadrangle interactions at the DI-DII interface of L-type channels as the molecular basis for voltage-dependent facilitation.

The paper demonstrates that computations and asynchronous states can occur in neural networks without spiking through subthreshold voltage fluctuations, using biophysically detailed Hodgkin-Huxley neurons.

This study examines the biophysical effects of a Cav2.3 channel mutation (L228P) linked to DEEs using whole-cell patch-clamp, finding a shift in voltage-dependent activation and inactivation towards hyperpolarized potentials.