PathologybioRxivPreprint
Infection of 5xFAD mice with a mouse-adapted SARS-CoV-2 does not alter Alzheimer's disease neuropathology yet induces wide-spread changes in gene expression across diverse cell types
Susana Furman, Latifa Zayou, Kate Inman Tsourmas…·Thomas E. Lane
This study infects 5xFAD mice with SARS-CoV-2 and finds no change in Alzheimer's pathology but widespread gene expression changes in multiple cell types.
DOI 10.64898/2025.12.19.695600