Cell BiologybioRxivPreprint
Clade B serpins promote direct basal-to-goblet cell differentiation in airways of patients with chronic obstructive pulmonary disease
Tiffany S. Tufenkjian, Jessica Bailey Blackburn, David Nichols…·Bradley W. Richmond
The paper identifies clade B serpins as drivers of basal-to-goblet cell differentiation in COPD, linking them to goblet cell hyperplasia and inflammatory signaling.