Immune History Modifies Disease Severity to HPAI H5N1 Clade 2.3.4.4b Viral Challenge
Pamela H. Brigleb, Bridgett Sharp, Ericka Kirkpatrick Roubidoux…·Stacey Schultz‐Cherry
The paper shows that pre-existing immunity from H1N1 infection or vaccination can protect against lethal HPAI H5N1 clade 2.3.4.4b challenge in mice and ferrets, independent of hemagglutination inhibition titers.