Katrina Callan

The paper identifies a bacterial mechanism, CART, where Rae1 endonuclease cleaves mRNA from collided ribosomes to enable trans-translation and rescue stalled ribosomes.

This study identifies YebC2 as a translation factor that resolves ribosome stalling at polyprolines independently of EF-P and YfmR in B. subtilis.

This paper shows RqcH enables bacterial survival without non-stop ribosome rescue factors by tagging stalled peptides for removal, and reveals widespread conservation of ribosome rescue pathways across bacterial species.