Cassidy R. Prince

The paper identifies a bacterial mechanism, CART, where Rae1 endonuclease cleaves mRNA from collided ribosomes to enable trans-translation and rescue stalled ribosomes.

The paper identifies SNOR, a ribosome-associated factor in S. pombe, that enables translation restart after cellular dormancy induced by glucose depletion.

The paper surveys sporulation genes in Paenibacillus genomes, finding a conserved phosphorelay but a unique transmembrane-domain-containing Spo0B variant present in 92% of species.

The paper analyzes >12,000 bacterial genomes to study the conservation and evolution of the programmed ribosomal frameshift in prfB, finding it was present in the last common ancestor of bacteria and linked to stop codon usage.

This study identifies YebC2 as a translation factor that resolves ribosome stalling at polyprolines independently of EF-P and YfmR in B. subtilis.

This study identifies SNPs in enterotoxin genes that better predict cytotoxicity of B. cereus group strains in Caco-2 cells than enterotoxin gene presence alone.

This paper shows RqcH enables bacterial survival without non-stop ribosome rescue factors by tagging stalled peptides for removal, and reveals widespread conservation of ribosome rescue pathways across bacterial species.