Author

Denise Kalos

Moffitt Cancer CenterORCID 0009-0008-0576-3222Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1

Frequent Co-Authors

Andriy MarusykiD· 1 shared Bina DesaiiD· 1 shared Biwei CaoiD· 1 shared Bruna PelliniiD· 1 shared Christopher M. WilsoniD· 1 shared Dung‐Tsa Chen· 1 shared Eric B. HauraiD· 1 shared Gina S. Nazario· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Andriy MarusykORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 17, 2024

Trastuzumab deruxtecan combination strongly enhances responses and overcomes sotorasib resistance in KRASG12C-mutant NSCLC

Hilal Özakıncı, Bina Desai, Denise Kalos…·Bruna Pellini

This study shows that combining trastuzumab deruxtecan with sotorasib improves responses in KRASG12C-mutant NSCLC and overcomes resistance, but HER2 expression levels influence treatment effectiveness.

2 citations

humanproteomics

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BioinformaticsBioinformaticsPeer-reviewedDec 29, 2021

Efficient gradient boosting for prognostic biomarker discovery

Kaiqiao Li, Sijie Yao, Zhenyu Zhang…·Xuefeng Wang

This paper introduces Xsurv, an R package using XGB and LGB for survival analysis, showing it outperforms traditional methods in biomarker discovery for cancer prognosis.

76 citationstop 2%

DNA methylationmachine learning (classical)

𝕏 PostBluesky