Author

Zach Sisson

The Align FoundationORCID 0009-0008-0615-4859Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Zach Sisson1 paper

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Assay:protein sequence· 1

Frequent Co-Authors

Aviv SpinneriD· 2 shared Dana L. CortadeiD· 2 shared David RossiD· 2 shared Svetlana P. IkonomovaiD· 2 shared Amanda Reider ApeliD· 1 shared Andi DhrosoiD· 1 shared Anjali ChadhaiD· 1 shared Catherine BaranowskiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersBioengineering

Aviv SpinnerORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintMay 29, 2026

GROQ-seq Datasets Across Transcription Factors (LacI, RamR, VanR), T7 RNA Polymerase and TEV Protease

Aviv Spinner, Shwetha Sreenivasan, James R. McLellan…·Catherine Baranowski

The paper introduces GROQ-seq, a high-throughput platform for linking protein function to sequencing data, and presents pilot datasets for transcription factors, polymerases, and proteases.

3 citations

E. colibulk RNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMay 12, 2026

Unified sampling framework and experimental benchmarking of sequence- and structure-based protein models

Aviv Spinner, Pascal Notin, Samuel P. Berry…·Debora S. Marks

The paper benchmarks sequence- and structure-based protein models using a unified framework, showing structure-based models outperform others in generating functional variants.

DOI 10.64898/2026.05.08.723784

protein sequencebenchmark study

𝕏 PostBluesky