Author

Ethan Belrose

Queen's UniversityORCID 0009-0008-0814-9172Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:transformer / foundation model· 1

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Kody A. KluptiD· 1 shared Zongchao JiaiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiochemistry

Kody A. KluptORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintDec 10, 2024

Development of a De Novo Protein Binder that Inhibits the Alpha Kinase eEF2K

Kody A. Klupt, Ethan Belrose, Zongchao Jia

The paper develops a de novo protein binder, CAM1, that inhibits eEF2K, an alpha kinase, with nanomolar affinity and comparable efficacy to a small molecule inhibitor.

DOI 10.1101/2024.12.10.627789

humanprotein structure

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