Author

Luis Agustin E. Pilapil

University at Buffalo, State University of New YorkORCID 0009-0008-0833-7536Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Gunes Ekin Atilla‐GokcumeniD· 1 shared Shweta ChitkaraiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperCell Biology

Gunes Ekin Atilla‐GokcumenORCID

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1 paper

Recent·Most cited

Cell BiologyRSC Chemical BiologyPeer-reviewedJan 1, 2026

Inhibition of Acid Sphingomyelinase Links Sphingolipid Remodeling to Necroptotic Cell Death

Luis Agustin E. Pilapil, Shweta Chitkara, Gunes Ekin Atilla‐Gokcumen

This study identifies acid sphingomyelinase (ASMase) as a key regulator of ceramide levels during necroptosis, showing that its inhibition reduces membrane permeability by impairing MLKL pore formation.

DOI 10.1039/d6cb00087h

experimental assayhost-pathogen & immune response

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