Run‐Zhou Yang

This study uses optogenetics to control cAMP and HCN channels in cardiac and Parkinson's disease models, showing effects on heart rate and motor function.

This study develops and applies methodologies to manipulate cardiomyocyte physiology in vitro and in vivo, revealing effects of optogenetic and chemogenetic tools on heart rate and calcium dynamics.

This study uses optogenetic methods to induce cell death by manipulating mitochondrial function through light-sensitive proteins, showing potential for therapeutic applications in diseases with abnormal cell survival.

This study shows that STX12 deficiency leads to mitochondrial dysfunction, mtDNA release, and activation of the cGAS-STING and Type I interferon pathways in mice, contributing to lethal inflammation.