Author

Hannah Finan

Edinburgh Cancer ResearchORCID 0009-0008-2153-2096Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Cristina Rubio-Ramon· 2 shared Duncan SprouliD· 2 shared Francesca Taglini· 2 shared Hazel Davidson‐Smith· 2 shared Ioannis KafetzopoulosiD· 2 shared Jimi C. WillsiD· 2 shared Kamila Irena MusialikiD· 2 shared Andrew J. FinchiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersGenetics

Cristina Rubio-Ramon

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2 papers

Recent·Most cited

GeneticsEMBO ReportsPeer-reviewedJan 30, 2024

DNMT3B PWWP mutations cause hypermethylation of heterochromatin

Francesca Taglini, Ioannis Kafetzopoulos, Willow Rolls…·Duncan Sproul

This study shows that DNMT3B PWWP mutations cause hypermethylation of heterochromatin marked by H3K9me3, disrupting DNA methylation homeostasis and contributing to ICF syndrome, cancer, and aging.

20 citations

humanDNA methylation

𝕏 PostBluesky

GeneticsNature CommunicationsPeer-reviewedJan 29, 2021

De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands

Roza H. Ali Masalmeh, Francesca Taglini, Cristina Rubio-Ramon…·Duncan Sproul

The paper shows de novo DNA methyltransferases in colorectal cancer target H3K36me3-marked CpG islands, similar to normal tissues, rather than sequence-specific CpG islands.

55 citations

humanDNA methylation

𝕏 PostBluesky