Author

Spyridoula Mitsikosta

Stockholm UniversityORCID 0009-0008-2387-0507Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

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Ane MetolaiD· 1 shared Fátima Pardo‐ÁvilaiD· 1 shared Gunnar von HEIJNEiD· 1 shared Justin M. WesterfieldiD· 1 shared Michael LevittiD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperMolecular Biology

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1 paper

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedOct 5, 2026

Quasi-continuous cotranslational compaction and folding of a multidomain protein

Spyridoula Mitsikosta, Justin M. Westerfield, Fátima Pardo‐Ávila…·Ane Metola

This study uses Force Profile Analysis to examine the cotranslational folding of Firefly luciferase, revealing a complex, quasi-continuous folding process with multiple intermediate steps.

DOI 10.1038/s41467-026-78090-y

protein structureexperimental assay

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