Author

Pauline J. Schipper

Leiden University Medical CenterORCID 0009-0008-2402-0897Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Adriaan Erasmus BassoniD· 1 shared Annefleur D. O. HenseniD· 1 shared Annemarie MJ Wensing· 1 shared Anoecim Robecca Geelen· 1 shared Céline HarmanusiD· 1 shared Christine VoorveltiD· 1 shared Ebrahim VariavaiD· 1 shared Ed J. KuijperiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Adriaan Erasmus BassonORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 25, 2026

Persistent Microglial HIV Infection Drives Neuroinflammation Despite Viral Suppression: Insights from Rapid Postmortem Brain Biopsies

Marieke M. Nühn, Nadia Sabet, Nanouk Zuidmeer…·Jori Symons

The paper quantifies HIV persistence in microglia and shows transcriptional changes in microglia and other cell types despite ART, highlighting microglia as a key target for CNS HIV cure strategies.

DOI 10.64898/2026.05.20.726582

humanbulk RNA-seq

𝕏 PostBluesky

MicrobiologyThe Journal of Infectious DiseasesPeer-reviewedDec 3, 2025

Manufacture of Clostridioides difficile spores for experimental infection of human volunteers

Annefleur D. O. Hensen, Céline Harmanus, Christine Voorvelt…·Wiep Klaas Smits

This paper describes a GMP-compliant process for producing C. difficile spores for use in controlled human infection models.

DOI 10.1093/infdis/jiaf612

C. elegansexperimental assay

𝕏 PostBluesky