Author

Madeline L. Sheahan

University of ChicagoORCID 0009-0008-3152-8381Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:metagenomics· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Laurie E. ComstockiD· 2 shared Adriana Gutiérrez-Camacho· 1 shared Ákos T. KovácsiD· 1 shared Fitnat H. YildiziD· 1 shared Kathryn Hutt· 1 shared Katia FloresiD· 1 shared Leila TuzlakiD· 1 shared Leonor García-BayonaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

Laurie E. ComstockORCID

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2 papers

Recent·Most cited

MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedApr 7, 2026

Antagonism by the Type VI secretion system of Bacteroides fragilis is controlled by a TetR family regulator and released small molecule

Leila Tuzlak, Téa E. Pappas, Michael J. Coyne…·Laurie E. Comstock

This paper identifies a small molecule regulated by a TetR family regulator that controls the GA3 T6SS and immunity genes in Bacteroides fragilis, enabling coordinated antagonism and defense.

2 citationstop 3%

bacteria (other)proteomics

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MicrobiologybioRxivPreprintApr 29, 2024

A pervasive large conjugative plasmid mediates multispecies biofilm formation in the intestinal microbiota increasing resilience to perturbations

Leonor García-Bayona, Nathania Said, Michael J. Coyne…·Laurie E. Comstock

The paper identifies a large conjugative plasmid that promotes multispecies biofilm formation in the gut microbiota, enhancing resilience to environmental stressors.

5 citations

humanmetagenomics

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