Michael J. Coyne

The paper shows that host genetics affects the colonization and gene expression of Lactobacillaceae bacteria in the small intestine, with differences observed between C57BL/6J and BALB/cJ mice.

This paper identifies a small molecule regulated by a TetR family regulator that controls the GA3 T6SS and immunity genes in Bacteroides fragilis, enabling coordinated antagonism and defense.

This study identifies DNA-utilization loci in gut Bacteroidales that metabolize exogenous DNA into deaminated nucleobases, revealing a conserved pathway with implications for host-microbe interactions.