Author

Nicola K. Auld

University of WollongongORCID 0009-0008-3737-183XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Antoine M. van OijeniD· 2 shared Heath W. EcroydiD· 2 shared Nicholas R. MarzanoiD· 2 shared Shannon McMahoniD· 2 shared Bailey SkewesiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersBiophysics

Antoine M. van OijenORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJun 2, 2026

Single-molecule visualisation of human Hsp70-driven conformational remodelling during stress

Bailey Skewes, Shannon McMahon, Nicola K. Auld…·Heath W. Ecroyd

This study uses smFRET to visualize how Hsp70 remodels misfolded Fluc under chemical and heat stress, revealing conformational expansion and Hsp110-driven release for productive folding.

DOI 10.64898/2026.06.01.729260

humanfluorescence / live-cell microscopy

𝕏 PostBluesky

BiochemistryProtein SciencePeer-reviewedSep 13, 2025

Competing chaperone pathways in α-synuclein disaggregation and aggregation dynamics

Nicola K. Auld, Shannon McMahon, Nicholas R. Marzano…·Heath W. Ecroyd

This study investigates the interaction between sHsps and Hsp70 chaperones in α-synuclein disaggregation and aggregation, finding no synergy and potential antagonism between the chaperone classes.

4 citations

experimental assay

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