Author

Masatoshi Haga

Rohto Pharmaceutical (Japan)ORCID 0009-0008-4600-3000Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

Keita IidaiD· 1 shared Mariko OkadaiD· 1 shared Sachiko SekiyaiD· 1 shared Sawa YamashiroiD· 1 shared Shun KimuraiD· 1 shared Tatsuya ShimizuiD· 1 shared Tetsutaro KikuchiiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 11 mutual co-author links

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1 shared paperSystems Biology

Keita IidaORCID

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2 papers

Recent·Most cited

BioengineeringEMBO ReportsPeer-reviewedApr 1, 2026

The heterogeneity of dermal mesenchymal cells reproduced in skin equivalents regulates barrier function and elasticity

Shun Kimura, Sachiko Sekiya, Sawa Yamashiro…·Tatsuya Shimizu

This study creates human skin equivalents with heterogeneous dermal mesenchymal cells that enhance skin barrier function and elasticity, enabling in vitro drug testing.

1 citation

humanorganoid / primary culture

𝕏 PostBluesky

Systems BiologybioRxivPreprintJul 18, 2023

Positive and negative feedback regulation of the TGF-β1-SMAD4 axis explains two equilibrium states in human skin aging

Masatoshi Haga, Keita Iida, Mariko Okada

This study identifies THBS1 and FMOD as positive and negative regulators of the TGF-β1-SMAD4 axis in human skin aging, revealing two equilibrium states through mathematical modeling and omics analyses.

DOI 10.1101/2023.07.18.546970

humanbulk RNA-seq

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